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Lymphohemangioma, or lymphohaemangioma, (from Latin lympha 'water', Greek αίμα (haima) 'blood', ἀγγεῖον (angeion) 'vessel', and –ωμα (–oma) 'tumor') is a disease characterized by swelling of the lymph nodes and blood vessels. It is variously described as a "mixture of clear fluid and blood-filled cysts", a mass of abnormal swollen veins and lymph nodes, or a tumorous growth of lymph and blood vessels. It is also sometimes described as a misnomer for combined lymphatic and capillary malformation.

Signs and Symptoms
-Purplish thin walled lesions of cysts most commonly in the head or neck area

-Filled with blood and clear fluid

-Most commonly found in children up to 2 years old, however there are rare cases of adults experiencing this.

-It is named after the fluid that creates the cyst. Lymph is the fluid of the lymphatic system which is used to create the cyst. Hema refers to the blood which also fills up the area. Oma refers to the swelling which occurs in the specific cyst.

Pathophysiology
Lymphohemangiomas are considered benign tumors. They are abnormal congenital developments caused by bleeding or inflammation of the lymphatic system. The affected area is filled with lymph as well as blood causing swelling and the fluid to fill the area. The fluid may harden causing the benign tumor to form, made up of hardened lymph and blood in the affected area.

Cause
Lymphohemangioma is caused by by improper development of the lymphatic system and blood vessels. The cause of this improper development is unknown.

Lymphohemangioma commonly appears in and around the eyes and mouth, but may also occur in other areas, including the pelvis, urethra, bladder, and in the limbs. Amputation of extremities may be necessary if the disease renders the extremity non-functional.

Diagnosis
In lymphohemangiomas occurring in areas which are easily accessed, a section of the cyst will be removed and observed under a microscope. If it is found to contain lymphatic tissue as well as blood vessel it will be diagnosed as a lymphohemangioma. In areas which are not easily accessed such as rare cases of intestinal lymphohemangioma the section can be seen through a radiograph or ultrasound, however this commonly leads to misdiagnosis.

Treatment
Common forms of treatment currently are cryotherapy, sclerotherapy, and radiofrequencytherapy.

- Cryotherapy is used to freeze the area and attempts to freeze the tumor and allow for its death and easy removal.

- Sclerotherapy involves injection into either the blood or lymphatic vessels. This injection causes vasoconstriction of the area which allows the vessels to shrink and cut off fluid flow to the affected area.

- Radiofrequencytherapy is used after the pain in the nerve cells is cut off. It destroys the nerve fibers in the area affected which will then allow for the area to undergo surgery and removal with minimal pain.

Prognosis
The prognosis of lymphohemagioma is good. Chances of this issue reoccurring is extremely rare.

Epidemiology
Lymphohemangioma is extremely rare with roughly 90% of cases occurring in children under the age of 2.