User:JohnLloydScharf/Archive of 10/27/2011

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The Wikipedia tutorial is a good place to start learning about Wikipedia. If you have any questions, see the help pages, add a question to the village pump or ask me on my talk page. By the way, you can sign your name on Talk and discussion pages using four tildes, like this: &#126;&#126;&#126;&#126; (the software will replace them with your signature and the date). Again, welcome! JohnLloydScharf (talk) 08:36, 22 August 2011 (UTC) You need to check what I wrote. I am posting to those who understand population genetics, statistics, et cetera. So far the page in question is ruled by a consensus of one and sock puppets. I am making an effort to bring the edit wars to an end without sacrificing an article to content that is not verifiable and in contradiction to the references. Regarding my signature, I know I left a signature on your page. The content should have looked like this:

http://en.wikipedia.org/wiki/Haplogroup_J1_(Y-DNA)
Please review the map, the work of Tofanelli et al, Hassan et al, and comment in the discussions:

http://en.wikipedia.org/wiki/File:HG_J1_(ADN-Y)

http://hpgl.stanford.edu/publications/AJHG_2004_v74_p1023-1034.pdf http://ychrom.invint.net/upload/iblock/94d/Hassan%202008%20Y-Chromosome%20Variation%20Among%20Sudanese.pdf

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC384897/figure/FG1/ http://en.wikipedia.org/wiki/Haplogroup_J1_(Y-DNA)

http://en.wikipedia.org/wiki/Talk:Haplogroup_J1_(Y-DNA)

Essentially, the issue is whether J1 dominates in Sudan and the Caucasus at over 60%. John Lloyd Scharf 10:36, 23 August 2011 (UTC)

Wikiquette
I noticed you posted a report about another user at WT:Harassment. Sorry, but I had to remove that because that page is to discuss the WP:Harassment policy. The place to seek opinions from other editors about an incident like this is at WP:WQA ("Wikiquette assistance"—it has a gentle name to avoid sounding too officious). In a serious case, a report could be made at WP:ANI, however I would advice against that unless the case is really serious (like someone threatening legal action or physical intimidation). Johnuniq (talk) 00:52, 21 August 2011 (UTC)

It was about the use of vulgar language and threats by an Administrator. It is irresponsible. Locking down a page and claiming the Administrators will do the editing is another dodge. It is a nonconstructive device to avoid rather than deal with conflict resolution. What we have here is Buck passing and a failure to Administrate. JohnLloydScharf (talk) 01:07, 21 August 2011 (UTC)

The Administrators who lock down take no responsibility and abandon their duties. If they did, then they would adjudicate as dictated by these statements on the lockdown: ''

[[Image:Yes check.svg|20px]]STANDARD LOCKDOWN STATEMENT NOT ABIDED BY WHEN USED BY ADMINISTRATORS
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My Observation
Can does not mean will. I submitted two requests. Both were ignored and the lock down ends tomorrow with nothing resolved, other than someone who is not signed in can get the page locked down. It could just as well be the person who signs in who, by logging out, can pretend to be these others who just reveal an IPS. In the long term, it seems it does not matter what Wikipedia has for a stated policy. It is the practice which has built Wikipedia's reputation for accuracy and dependability. JohnLloydScharf (talk)

You can hunt down SNPs by using the following link:
http://www.ncbi.nlm.nih.gov/snp Note also the NT position rs2395182 is relative to the genome analysis is from the reference assembly. You can find the map here: In this map you will not that the SNP is extragenic, it is neither in DQA1 or DQB1. You can see the genetic positions of other genes. In the map you will see red squares, these are the position of diseases loci. The DQ4 specific marker is here:  There are no diseases currently associated with this marker.

Response

 * I keep all my genetic info online here.
 * I am actually more interested in the distribution of autosomal genetics from an archaeological perspective and, certainly, HLAs have play in that. The y.pestis plague seems to have an immunological component because many did not die of it. I have seen only one HLA population distribution paper, but it got me thinking.
 * I have no history of being Jewish, but my mtDNA and yDNA seem to ultimately track to one Sephardi group or another either in the Family Tree data. With the Armenian Holocaust data coming in, that may give more clues. All of this would be a surprise to my paternal half-brothers. I have located a paternal uncle's grandson. They have the Shurvington surname because of the my uncle was orphaned.
 * That is a bit strange because my maternal lineage seems to track back to the British Isles where there are plenty of H3, albeit a rare subclade. From my perspective, if it is beyond seven generations, it is highly unlikely you will have any ethnic autosomal genes left and my mother's side of the family is nearly twice that in the US South. So, I would not expect The Sephardi origins to be in the mtDNA.
 * Now, given all that, my father and his brothers survived the "Swine" flu in an orphanage, but their sister did not. In my pre-teens the flu would immediately push me into a high fever of more than 104 and less than 107. I have not had the flu as an adult. My father contracted polio, but my mother did not. She contracted and survived typhoid. As an infant I nearly died and was only saved from Scarlet fever (107)by that new antibiotic, penicillin. I survived whooping cough as well.
 * So, I am interested in the immunology connected with a cyclonic storm and possibly polio. My CCR5 came back "normal-normal." As far as I know, that is the settings most used on my washer/dryer. I will investigate that further. My guess is I do not have the delta 32 mutation and not a good prospect for bone marrow donor to someone with HIV.
 * I have been using SNPedia, but NBIC may help too. I am 60 years old and switched from goal of a BS in EE to Soc./Psy. in my third year. My third term of calculus was dismal, but my other classes were good. I still took rudimentary research classes in my fourth year, so I understand basic methodology along with the meaning of the probability and statistics. What I do know makes me think the conclusions reached by the papers is unwarranted and the number of samples used near useless. The methodology is worse than if you used ysearch.org to do a paper. They use stats generated from math used for random samples and their sampling is non-random.
 * I hope you read fast so you do not get bored with my inane ramblings. John Lloyd Scharf 20:04, 24 August 2011 (UTC)

R2R

 * There was an influx of NE mediterranean HLA types into the Belgium population that carries some distinct Armenia markers. Historical accounts suggest that many migrated to Britain at the time of the Roman expansion into channel region. Many European markers can be traced to SE Europe, although at great temporal distance (2000 to 10000) years. These markers are enriched in SE England and diminished in Wales, Ireland, NW England, and Scotland. Given the affinity of jews with NE mediterranean peoples, specific Jewish/Anglo genetic similarities are not expected. Jews were also common in Germany prior to the medieval, many underwent forced conversion to catholicism.PB666 yap 20:26, 24 August 2011 (UTC)
 * I call Jews who were forced to convert, converted just to avoid the struggle,ended up in adoption by gentiles, or the result of some other Non-Paternal Event [NPE] a CryptoJew. I have one ancestor who immigrated from Germany 200+ years ago and the rest seem to be Gaelic. I looked at the descendants of some of my maternal ancestors. They seem to be R1b or I. Dirt is more common than R1b in the US, but not by much. Perhaps it came through the Childress lineage who were clannish in marriage, but they are mostly I haplogroup, so that may have disguised the origins out of Anglia for me. There may be many Jews/Female who intermarried rather than go in the Expulsion. Perhaps that is where the "enriched" markers come from. Still, I have only one mtDNA full genome sequence match and that is with someone who traces to "England," so you may be correct. My sequence is at http://www.ncbi.nlm.nih.gov/nuccore/JN020360 John Lloyd Scharf 21:02, 24 August 2011 (UTC)

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