User:Jordanyaq/sandbox

Medicinal Roles
Testican-1 is known to play a role in lapatinib resistance, which is a drug used to treat HER2-positive gastric cancer. Testican-1 is involved in the pathway for this drug, and leads to drug resistance when upregulated. When testican-1 levels are artifically reduced, sensitivity towards lapatinib was once again increased. This shows the potential for future use in combatting drug resistance.

Testican-1 has also shown to be useful when studying sepsis in patients. A study revealed that patients with more advanced sepsis exhibited higher levels of testican-1. This is useful in determining the severity of sepsis in a clinical setting and could allow healthcare professionals to formulate a better treatment plan.