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History of agricultural science looks at the scientific advancement of techniques and understanding of agriculture. Scientific study of fertilizer was advanced significantly in 1840 with the publication Die organische Chemie in ihrer Anwendung auf Agrikulturchemie und Physiologie (Organic Chemistry in Its Applications to Agriculture and Physiology) by Justus von Liebig. One of Liebig's advances in agricultural science was the discovery of nitrogen as an essential plant nutrient.