User:Joshuajwhiting/Comprehensive Two Dimensional Gas Chromatography

Comprehensive Two Dimensional Gas Chromatography (GCxGC)is an emerging technique in the area of gas chromatography originally developed by Professor John Phillips at Southern Illinois University in Carbondale, IL. The technique consists of two or more GC columns connected in series by a modulator. The modulator collects small aliquots of the efluent from the first column and then injects them onto the second column where a complete second separtation occurs prior to the injection of the next alliquot. The technique offers three commonly sited advantages over a traditional one dimensional separation.

1.) An increase in analyte detectability - most commercially available systems on the market utilize a thermal modulator to collect and reinject the effluent from the first column. In this method analytes are focused on a cold spot of the column