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Underlying causes include gastric ulcers, duodenal ulcers, appendicitis, gastrointestinal cancer, cholecystitis (gallbladder inflammation), diverticulitis, inflammatory bowel disease, superior mesenteric artery syndrome, trauma, vascular Ehlers–Danlos syndrome, and ascariasis. Typhoid fever, non-steroidal anti-inflammatory drugs, ingestion of corrosives may also be responsible.

Eating multiple magnets can also lead to perforation if the magnets attract and stick to one another through different loops of the intestine.

copied from Gastrointestinal perforation