User:Jquick2019/Evaluate an Article

Which article are you evaluating?
Kozak consensus sequence

Why you have chosen this article to evaluate?
I was clicking through links to find something in the realm of molecular biology and a link the the article caught my eye as I was skimming through the Methionine page. I personally think consensus sequences are cool and it was interesting to read about the eukaryotic equivalent of the Shine-Dalgarno sequence that I learned about in Prokaryotic Molecular Biology.

The Kozak Consensus Sequence is a pattern in the DNA sequence surrounding the start codon which regulates gene transcription. Any deviation from this sequence leads to a lowered effectiveness in gene transcription for eukaryotes.

Overall, this article seems to require a large amount of background knowledge for one to be able to understand it. I think it would be helpful for a layperson if there was resource attached to help understand some of the nomenclature better. (Note: after reading it over, the article does actually do what I just suggested.)

Evaluate the article

 * The lead is concise and informative.
 * The first sentence introduces the sequence well.
 * In it's current state, it does not seem to introduce the "Differences from bacterial initiation" section of the article. Further information on the existence of other consensus sequences may help with this.
 * The content of the article is up to date with a range of sources from the original work by Kozak to more modern work from 2019
 * The link for source 41 does not work. I will look into fixing this tomorrow.
 * The article maintains a neutral tone throughout, with minor hiccups in some places. This article does not mention any discourse on to the validity of this sequence, and it mentions how it is used to identify the location of start codons in eukaryotes.
 * Overall, the article is well laid out. I think it might help for readability if the sequence section was rearranged a little. In its current state, the actual sequence is referenced in the second sentence of a paragraph with a numbered list explaining it below. This draws attention away from the sequence itself and makes it difficult to see what the numbered list is referencing. The simple solution would be to add a line break before defining the sequence.
 * Some additions and rewording could help with the See Also section, such as the description for mRNA in the section and the addition of
 * The figure in the sequence section uses bits as the y axis without properly defining what that is. It is also very difficult to see the relative sizes of letters and understand what this means. For some data points, such as 1, 18, and 20, it is impossible to even see all of the letters to be able to compare the sizes of said letters or know what the frequency distribution of those letters is for that position. It also does not include the start codon in the y-axis even though it defines it as part of the sequence in the same section.
 * Looking though the talk page shows that this article was also worked on as a class project.
 * At some point this article was merged with another article also about this same sequence.