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Honokiol and its structural isomer magnolol are both compounds isolated from the bark of trees belonging to the Family Magnoliaceae.

Use in Traditional Medicine
Bark from various species of magnolia trees has been used in traditional Asian medicine for centuries. Use of the magnolia tree is particularly popular in traditional Chinese medicine as well as Japanese Kampo. In China, magnolia bark is called Houpu. A popular medicinal compounds containing honokiol from China is Banxia Houpu Tan (半夏厚朴丸); while in Japan, there are Saiboku-to(柴朴湯) and Hange-koboku-to (半夏厚朴湯). These compounds have been used to treat gastrointestinal disorders, anxiety, depression, insomnia, and many other disorders.