User:Juan Ramon Ruiz Hervas/sandbox

= Immunogenic gluten peptides (GIP) =

== GIP are fragments of gluten proteins resistant to gastrointestinal digestion that cause a cascade of immunological reactions in the celiac patient. The resistance of gluten peptides to gastrointestinal digestion ensures that a significant portion of the gluten peptides ingested are excreted. Therefore, recovery of measurable amounts of the immunotoxic fraction in stool or urine samples would indicate that there has been gluten consumption. Therefore, the presence of GIP in feces and urine is a direct marker for the surveillance and monitoring of the gluten-free diet (DSG) in the short and long term. ==

Function
== GIPs are excreted through faeces and urine by anyone who ingests gluten, whether they have celiac disease, allergy to wheat, sensitivity to non-celiac gluten or a person without any disorder related to gluten intake. However, its intake will only produce immune reactions in people with these disorders. ==

Pathology
== The detection of GIP constitutes a new method for the general monitoring of celiac disease and sensitivity to non-celiac gluten, avoiding the consequences derived from the inadvertent intake of gluten. It has been shown in different scientific articles that the majority of transgressions of the gluten-free diet are not detected by the presence of symptoms or by the serological levels of antitransglutaminase antibodies or antigliadin deaminated. ==