User:Julie Vacková

Infectious tolerance Infectious tolerance is also known as regulatory tolerance or dominant immune suppression. In 1971 was this term originally used by Gershon and Kondo in connection with suppression of naive lymphocyte populations by cells with some regulatory function. After that it was expanded upon by Waldman´s group in 1993 (For 3 years the article was not admitted!). Nowadays the term "infectious tolerance" describe a proces where tolerance-inducing state is transferred from one cell population to another. Infectious tolerance is irreplaceable part of inflammatory regulation and immune homeostasis which is mediated by regulatory T cells (Treg) CD4 CD25 FoxP3 positive.

Treg cells are able to suppress effector lymphocytes by many ways.