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Ho Yow served as consulate general during San Francisco plague of 1900–1904. Ho Yow was born in Hong Kong to a wealthy Guangzhou family.

At the age of 28, Ho was appointed as vice consul of the San Francisco Chinese Consulate to general consul Chang Yin Tang in 1987. Ho was soon promoted to consulate general, with the goal increasing trade relations between the United States and China, serving to the prosperity of Chinatown merchants. Notably in 1899, Ho organized a successful Chinese parade during San Francisco's Fourth of July Celebration.

In May 16 1900, after confirmation of several Chinese deaths due to bubonic plague, Ho along with leaders of the San Francisco Chinese community recommended vaccinations to their associations and tongs. This recommendation was met with resistance, however Consul Ho and Six Companies tried to calm the concerns. Despite the effort, only 53 Chinese were vaccinated compared to the 530 Japanese and 234 of other races.

Six Companies had filed grievances against Ho, and sent a list of complaints against Ho to the Chinese Imperial government. One of the complaints was the taking of bribes. Another concern was his lack of aggression during the debates on extending the Chinese Exclusion Act. The Chinese Exclusion Act was extended for 10 more years. Ho's title as consulate general was recalled by the Imperial government in 1902.