User:Kaitlynwu18/Choose an Article

Article Selection
Please list articles that you're considering for your Wikipedia assignment below. Begin to critique these articles and find relevant sources.

Option 1

 * Article title
 * Multiple cloning site - Categories: Genetics stubs, genetics


 * Article Evaluation
 * Quality: Stub-Class
 * Importance: Mid-Importance
 * The article gives a decent overview of multiple cloning sites in general. However, much greater detail can be provided for this topic, such as more potential uses and applications of the multiple cloning site.


 * Sources
 * "Multiple-cloning-site plasmids for the rapid construction of recombinant poxviruses," 1985, Boyle, David B., Barbara EH Coupar, and Gerald W. Both , primary
 * Development of multiple cloning site cis-vectors for recombinant adeno-associated virus production, 2002, Yue Y, Dongsheng D. , primary
 * Engineering a minimal cloning vector from a pUC18 plasmid backbone with an extended multiple cloning site, 2019, Staal J, Alci K, De Schamphelaire W, Vanhoucke M, Beyaert R. , primary
 * Citations:
 * Boyle, David B., Barbara EH Coupar, and Gerald W. Both. "Multiple-cloning-site plasmids for the rapid construction of recombinant poxviruses." Gene 35.1-2 (1985): 169-177.
 * Yue Y, Dongsheng D. Development of multiple cloning site cis-vectors for recombinant adeno-associated virus production. Biotechniques. 2002 Sep;33(3):672, 674, 676-8. doi: 10.2144/02333dd03. PMID: 12238777.
 * Staal J, Alci K, De Schamphelaire W, Vanhoucke M, Beyaert R. Engineering a minimal cloning vector from a pUC18 plasmid backbone with an extended multiple cloning site. Biotechniques. 2019 Jun;66(6):254-259. doi: 10.2144/btn-2019-0014. Epub 2019 May 24. PMID: 31124712.
 * Staal J, Alci K, De Schamphelaire W, Vanhoucke M, Beyaert R. Engineering a minimal cloning vector from a pUC18 plasmid backbone with an extended multiple cloning site. Biotechniques. 2019 Jun;66(6):254-259. doi: 10.2144/btn-2019-0014. Epub 2019 May 24. PMID: 31124712.

Option 2

 * Article title
 * Recombinant virus - Categories: Virology, Influenza


 * Article Evaluation
 * Quality: Stub-Class
 * Importance: Mid-Importance
 * This article is extremely sparse and could use a major workup to go into much more depth on the topic. Real-life examples of recombinant viruses can be added to provide some context, as well as the generation of recombinant viruses.


 * Sources
 * "Western equine encephalitis virus is a recombinant virus," 1988, Hahn, Chang S., et al. , primary
 * Generation of Recombinant Vaccinia Viruses, 2015, Wyatt LS, Earl PL, Moss B. , primary
 * New natural intergenotypic (2/5) recombinant of hepatitis C virus, 2007, Legrand-Abravanel F, Claudinon J, Nicot F, Dubois M, Chapuy-Regaud S, Sandres-Saune K, Pasquier C, Izopet J. , primary
 * Citations:
 * Hahn, Chang S., et al. "Western equine encephalitis virus is a recombinant virus." Proceedings of the National Academy of Sciences 85.16 (1988): 5997-6001.
 * Wyatt LS, Earl PL, Moss B. Generation of Recombinant Vaccinia Viruses. Curr Protoc Microbiol. 2015 Nov 3;39:14A.4.1-14A.4.18. doi: 10.1002/9780471729259.mc14a04s39. PMID: 26528782; PMCID: PMC5123791.
 * Legrand-Abravanel F, Claudinon J, Nicot F, Dubois M, Chapuy-Regaud S, Sandres-Saune K, Pasquier C, Izopet J. New natural intergenotypic (2/5) recombinant of hepatitis C virus. J Virol. 2007 Apr;81(8):4357-62. doi: 10.1128/JVI.02639-06. Epub 2007 Jan 31. PMID: 17267503; PMCID: PMC1866139.
 * Legrand-Abravanel F, Claudinon J, Nicot F, Dubois M, Chapuy-Regaud S, Sandres-Saune K, Pasquier C, Izopet J. New natural intergenotypic (2/5) recombinant of hepatitis C virus. J Virol. 2007 Apr;81(8):4357-62. doi: 10.1128/JVI.02639-06. Epub 2007 Jan 31. PMID: 17267503; PMCID: PMC1866139.

Option 3

 * Article title
 * Termination signal - Categories: DNA


 * Article Evaluation
 * Quality: Stub-Class
 * Importance: Low-Importance
 * This article is merely a few sentences long when much more can be discussed on the topic. It fails to go into some important mechanisms that termination signals are involved with. A database of termination signals can be added, as well as some mechanisms that include the involvement of termination signals.


 * Sources
 * "Cloning and analysis of strong promoters is made possible by the downstream placement of a RNA termination signal," 1981, Gentz, Reiner, et al. , primary
 * Physiological mechanisms of signal termination in biological systems, 2012, Ligeti, E., Csépányi-Kömi, R. and Hunyady, L. , primary
 * The translational termination signal database, 1993, Chris M. Brown, Mark E. Dalphin, Peter A. Stockwell, Warren P. Tate , primary
 * Citations:
 * Gentz, Reiner, et al. "Cloning and analysis of strong promoters is made possible by the downstream placement of a RNA termination signal." Proceedings of the National Academy of Sciences 78.8 (1981): 4936-4940.
 * Ligeti, E., Csépányi-Kömi, R. and Hunyady, L. (2012), Physiological mechanisms of signal termination in biological systems. Acta Physiol, 204: 469-478. https://doi.org/10.1111/j.1748-1716.2012.02414.x
 * Chris M. Brown, Mark E. Dalphin, Peter A. Stockwell, Warren P. Tate, The translational termination signal database, Nucleic Acids Research, Volume 21, Issue 13, 1 July 1993, Pages 3119–3123, https://doi.org/10.1093/nar/21.13.3119
 * Chris M. Brown, Mark E. Dalphin, Peter A. Stockwell, Warren P. Tate, The translational termination signal database, Nucleic Acids Research, Volume 21, Issue 13, 1 July 1993, Pages 3119–3123, https://doi.org/10.1093/nar/21.13.3119