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The big-eared woodrat (Neotoma macrotis) is a species of rodent in the family Cricetidae. Closely related to, and formerly included in the species Neotoma fuscipes, it occurs from northern Baja California northward to the California Coast Ranges west and south of the Salinas Valley and in the Sierra Nevada to the South Fork American River. A study of the species found the "Bear Canyon" virus, a mammarenavirus, traditionally associated with the California mouse, is actually passed by the big-eared woodrat before host-jumping to the California mouse.