User:Kanaayah/sandbox

Pyrogens have animal and non animal testing. The animal testing include the rabbit pyrogen test(RPT). In the RPT, Rabbits are injected with substances that are contaminated with bacteria The rabbits suffer from various issues including respiratory, circulatory and organ failure. The non-animals tests include human cells also known as the monocyte activation test (MAT) This testing serves as a replacement to the animal testing. When human blood is exposed to a substance, the MAT detects the pyrogens. Overall, the The MAT is known to be more sufficient that RPT.