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= Cystic Fibrosis = Cystic Fibrosis (CF) is a genetically inherited disease that commonly effects white populations at a rate of 1 in 2,500 to 3,500 newborns. The disease primarily effects the lungs, sweat glands, digestive system, and reproductive system. These effected organs & systems are exocrine glands, which when affected by Cystic Fibrosis create an overly thick, sticky mucus that prevents the transfer of ions and water in cells.

History
Current research dates the origins of the F508del gene between 4,000 to 5,000 years ago in southwestern Europe, along the lines of southern France and or Portugal. It is believed that during the Early Bronze Age migratory groups from the Bell Beaker culture made their way throughout western Europe at the time, and slowly introduced the mutation amongst the populations. Otherwise, the documentation before the 19th century for cystic fibrosis is very limited, and it was never directly referenced as a condition until recently. Instead it has been noted in literature through the medieval period and beyond such as the correlation between Changeling folk lore and children with CF.

The identification of the disorder did not gain much attention until the early 1900's, and evolving medical practices helped shine a light on unknown diseases at the time. The first pathological description of the disease was given in 1938 by Dorothy Anderson, M.D., giving a fully drafted medical report over it titled "Cystic Fibrosis of the Pancreas and Its Relation to Celiac Disease: a Clinical and Pathological Study" in the American Journal of Diseases of Children. Her recognition of the disease was how the name Cystic Fibrosis was coined.

(20th & 21st Century)