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Coiled-coil domain-containing protein 120 (CCDC120), also known as JM11 protein, is a protein that, in humans, is encoded by the CCDC120 gene. The function of CCDC120 has not been formally identified but there are indications that it may somehow be linked to Breast Cancer. Structural components, conservation, and interactions can be identified computationally but there has been little laboratory work on CCDC120.

Gene
The CCDC120 gene is located on human chromosome X, at Xp11.23. There are six different transcript variants of CCDC120 produced by alternative splicing.

Protein
The CCDC120 protein has four different isoforms, ranging from 618 to 696 amino acids in length. Isoform 1 is the longest isoform and is encoded by transcript 1 of the CCDC120 gene.

Paralogs
CCDC120 has 3 identifiable paralogs in humans, FERM domain Containing 4A, FERM domain Containing 4B, and C1orf106 (gene).

References in Scientific Literature
CCDC120 was found to be upregulated under pulsed electromagnetic fields in human osteoblastlike cells.

Patterns
The mRNA transcript of CCDC120 contains a 120bp repeat near the 3' end.