User:Kelseymoore130/sandbox

Article Critique:

-large focus on pathogenic strains and epidemiology

-shorter section on genetic diversity and evolution

-all citations linked and functioning properly

-no biased viewpoints

Article Draft:

I will add a section on the process of discovery of Vibrio cholerae and title it "History". This will include the various scientists involved as well as the impact it has had on world populations.

HISTORY

The discovery of Vibrio cholerae began in the early 19th century with English anesthesiologist, John Snow. Snow was able to make connections between the sewage systems of the London Soho District with the Cholera breakout of 1854. Following Snow's work, Italian anatomist, Filipo Pacini, was able to identify the "vibrations" found in the intestinal walls of Cholera victims. However, Pacini was never able to provide definitive proof of this Cholera causative agent. Robert Koch and his colleagues were the first to successfully isolate the bacteria in a pure culture. Noticing the bacteria could proliferate in soiled linens and damp environments, Koch was able to fuel the arguments for the germ theory of disease.

I will add to the "Genome" section to include the DNA recombination work done by Soler-Bistué.

GENOME

Gene location, in relation to the site of replication, has been linked to mRNA abundance within the cell. mRNA abundance affects cell growth rate of V. cholerae.

Lippi, D., & Gotuzzo, E. (2014). The greatest steps towards the discovery of Vibrio cholerae. Clinical Microbiology and Infection, 20(3).