User:Kendalse/GAB2

Project Proposal

By: Ashley Tran, Bryan Tan and Seth Kendall

Summary

Discovery
In this section we will give a basic overview of the history of the gene including its discovery and advances in our understanding of its function.

Importance
Description of the importance to cellular function of the protein.

Location
Description of the physical location of the GAB2 gene on the genome and any importance related to this.

Structure
Description of the structure of the GAB2 protein.

Function
More detailed description of the function of the protein in the cell.

Interactions
Descriptions of the various interactions of the GAB2 protein. Including interactions with Grb2, PTPN11, PLCG2, RICS, PIK3R1, CRKL, AKT1 and SHC1.

Association with Alzheimer’s Disease
Brief overview of the body of knowledge linking GAB2 to Alzheimer's Disease.