User:KevinBrownJHU/sandbox

= Sandbox Setup =

The Five Pillars

 * 1) This is an encyclopedia, not a dictionary, essay holder, or a platform for personal issues or controversial topics
 * 2) Articles should maintain a neutral point of view. Ideas should be presented, not points of view.
 * 3) Copyright needs to be respected. Content posted needs to be properly cited and shouldn't be copied wholesale or in part as that is plagiarism.
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 * 5) There are no hard rules for how things work. The spirit of the rules matters more than the literal wording of a rule.

Citations Practice
Performing genome assembly generally requires costly gene fragments produced through slow processes vi nucleotide synthesis and purification to remove potential problem sequences. A group at ASU figured out a way to do this same step with lower cost high-throughput assembly of gene fragments even when the quality of the oligos used is fairly poor. Utilizing ligation and careful temperature control of the initial cycles of the PCR the system can bring out high quality clones from low quality oligos.

Utilizing PCR and ligation, a group has shown that human papillomaviruses (HPV) is possible as a screen for early cancers.