User:Khinsonycp/Opioid use disorder

Buprenorphine[edit]
Buprenorphine/naloxone tablet Buprenorphine is a partial opioid receptor agonist. Unlike methadone and other full opioid receptor agonists, buprenorphine is less likely to cause respiratory depression due to its ceiling effect. Buprenorphine is known to be more at a risk of misuse or overdose compared to buprenorphine-naloxone and methadone, but treatment with buprenorphine may be associated with reduced mortality. Buprenorphine under the tongue is often used to manage opioid dependence. Preparations were approved for this use in the United States in 2002. Some formulations of buprenorphine incorporate the opiate antagonist naloxone during the production of the pill form to prevent people from crushing the tablets and injecting them, instead of using the sublingual (under the tongue) route of administration.

Methadone

Methadone is a drug used for both opioid overuse treatment and for chronic pain, it is known as a full opioid agonist. Methadone is the most common prescribed out of all the medications used for addiction; this is due to the fact that it has more advantages and less disadvantages than the other medications. Due to methadone's longer half life, it is much more challenging to prescribe dosage amounts compared to others. The long half life has good benefits, one of these benefits being the fact that if a dose is missed in the 24 hours of the last, the patient will not typically struggle with withdrawal symptoms quite yet. Methadone can be found in a couple different forms: tablet, oral solution, or an injection. The first time this medication was put to use was during World War II, it was a safer alternative to morphine.

My Thought: in this section of this article there is no heading with Methadone like the other medications, so methadone should be added.

See also[edit]

 * Benzodiazepine withdrawal syndrome
 * Doctor shopping
 * Hyperkatifeia, hypersensitivity to emotional distress in the context of opioid abuse
 * Physical dependence
 * Post-acute-withdrawal syndrome
 * Prescription drug abuse