User:Kirsten.bures/Dominance (genetics)/Kjindra Peer Review

General info

 * Whose work are you reviewing?

Kirsten.bures


 * Link to draft you're reviewing
 * https://en.wikipedia.org/wiki/User:Kirsten.bures/Dominance_%28genetics%29?veaction=edit&preload=Template%3ADashboard.wikiedu.org_draft_template
 * Link to the current version of the article (if it exists)
 * Dominance (genetics)

Evaluate the drafted changes
I think that it would be helpful to express how the misconceptions are false. Just stating them is one thing, but then stating the correct thing would be more helpful. Also, it might be helpful to add more sources for these statements since they are misconceptions.

Both dominant and recessive alleles can be extremely common or extremely rare. - This statement seems to be said multiple times within the misconceptions section. Maybe take out the repetition of this statement.

Alternate Allele Interactions

With haplosufficiency, I do not understand the definition that you wrote, or even if it is supposed to be a definition. Also, I am confused with how haplosufficiency connects to dominance. Maybe add a sentence to connect the two since it is under the dominance wiki page.

'''In Huntington's Disease, complete haploinsufficiency is seen in that a mutation causes a disease by a dominant effect of the mutant protein. -''' I would state where the mutation is or how it causes a disease for the mutant protein. Seems kind of vague. Also, with the next sentence you explain where the mutation is within the genome, so this would help to make the sentences connect.

Guiding Questions:

I think the article is a little hard to understand. As someone who has not been looking at this article for a long period of time, I do not quite understand all of the vocabulary. The vocabulary could very easily have been described earlier in the article, but it might help to add little summaries/definitions within these parts just incase people don't read the whole article. An example would be this sentence from the first paragraph. A "dominant" allele is dominant to a particular allele of the same gene that can be inferred from the context, but it may be recessive to a third allele, and codominant to a fourth.

Have you guys though about adding in images. Especially with the haplosufficiency parts, it might be helpful to have pictures or diagrams.