User:Knikritin/Tolaasin/JG8828 Peer Review

General info
Knikritin
 * Whose work are you reviewing?


 * Link to draft you're reviewing
 * https://en.wikipedia.org/wiki/User:Knikritin/Tolaasin/Bibliography?veaction=edit&preload=Template:Dashboard.wikiedu.org_bibliography
 * https://en.wikipedia.org/wiki/User:Knikritin/Tolaasin?veaction=edit&preload=Template:Dashboard.wikiedu.org_draft_template
 * Link to the current version of the article (if it exists)
 * Tolaasin
 * Link to the current version of the article (if it exists)
 * Tolaasin

Evaluate the drafted changes
The lead of "Tolaasin" does not reflect the changes made in the Sandbox article. The introductory sentence is useful in helping a general audience member understand what Tolaasin is and what its known for. Because it is an article stub, there are no major sections that can be described by the lead, nor does it include irrelevant items of information. While the lead is concise, it is highly technical, and would require the audience to have a general understanding of biology and chemistry to fully appreciate the description.

The added content is relevant to the topic and is partially up-to-date. One of the sources from Yun et al. is from 2023, but the other by Scherlach et al. is from 2013. There is no content that wouldn't belong on the stub. It does not address one of Wikipedia's equity gaps - the topic is not pertinent to the subject of historically underrepresented populations and topics.

The content is neutral and is not biased towards one side. It does not project over- or underrepresentation towards a particular viewpoint, and does not attempt to persuade the reader of a certain idea. Rather, the added content reflects a mechanistic pathway that tolaasin takes to disrupt the cellular membrane and additional information on inhibitors of tolaasin cytotoxicity.

Two sources were used to produce the added content on tolaasin. One article: "Biosynthesis and Mass Spectrometric Imaging of Tolaasin, the Virulence Factor of Brown Blotch Mushroom Disease" by Scherlach et al. in Chembiochem: A European Journal of Chemical Biology is from 2013. While the information itself is relevant to the mechanistic pathway and was cited numerous times, the findings themselves were from ten years ago. If possible, a more up-to-date paper regarding new insight on membranic disruption by tolaasin would be even more beneficial, whether it is from the same research group or another group doing similar work. Chembiochem has a moderate impact factor of 3.46. The other article: "Inhibition of Tolaasin Cytotoxicity Causing Brown Blotch Disease in Cultivated Mushrooms Using Tolaasin Inhibitory Factors." by Yun et al. is from 2023 and was published in Toxins, which has a moderate impact factor score of 4.2 in 2022, but the information provided by the group is useful because it provides new perspective on how various organic compounds, especially those found in food, may be useful in tolaasin inhibition.

The added content is concise and easy to read. It can still be refined to remove potential confusion - for instance, it may be confusing as to what the pores in the sentence "Tolaasin pores disrupt the cellular osmotic pressure, leading to membrane collapse" refers to. Does tolaasin have pores or does it generates pores on the membrane? Furthermore, the spelling of tolaasin should be double-checked. There is an extra space before the word "sucrose" in the last sentence that is not needed.

Overall, the new additions are helpful to the stub. They provide new information that otherwise would not have been known if a person was interested in learning more about tolaasin. However, it could still use further improvement with regards to the language used (technical vs layman terms), sources selected (using more relevant sources from the last 5 years in high impact factor journals), and general proofreading (spellcheck, spaces, etc).

Great work! Tolaasin sounds like an interesting thing in chemical biology/toxicology research. - Jonathan (JG8828)