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The San Giobbe Altarpiece (Italian: Pala di San Giobbe) is a c. 1487 altarpiece in oils on panel by the Venetian Renaissance painter Giovanni Bellini. Inspired by a plague outbreak in 1485, this sacra conversazione painting is unique in that it was designed in situ with the surrounding architecture of the church (a first for Bellini), and was one of the largest sacra conversazione paintings at the time. Although it was originally located in the Church of San Giobbe, Venice, it is now in the Gallerie dell'Accademia in Venice after having been stolen by Napoleon Bonaparte.

Creation
Just prior to 1478, Giovanni Bellini was commissioned to paint the altarpiece by an unknown individual from the Scuola di San Giobbe, to be placed opposite the Martini Chapel of the soon-to-be consecrated Church of San Giobbe. The friars and sisters of the San Giobbe Hospice had founded the Scuola di San Giobbe and replaced an old oratory dedicated to Job with a new church dedicated to both St. Job and St. Bernardino. This was strongly suggested by the confraternity's patron, the doge Cristoforo Moro.[1] This altarpiece marks the first time Bellini used the concept of creating an illusionary space to house a sacra conversazione that appears as though it is an extension of the church architecture itself, and honored St. Job with the position closest to the Christ child. The painting was designed in situ to incorporate the architecture of the Church of San Giobbe; the arches inside the painting match in perspective and design the marble arches of the church framing the painting.[1] Because the Church of San Giobbe did not have two chapels, only the Martini Chapel and an empty space opposite the chapel, the altarpiece was painted in order to create a space that would illusionistically balance the church with “two” chapels on either side. Hence the piece's size and detailed visual description of the perspective in fictive space was intended to serve as a second chapel, and the perspective, along with the similar framing within the painting and surrounding the painting, would give that proper illusion.[2]