User:Leannefogarty/sandbox

Article Evaluation on Hormone Article

Content


 * Article as a whole has a lot of complex terms that the general public might not understand
 * Under the section "receptors", I feel like they should clarify why certain hormones are unable to pass through the plasma membrane to allow the general public to understand that molecules with hydrophilic portions will be unable to get through the hydrophobic tails of the phospholipid membrane. They explain it for steroids and other lipid-soluble hormones and not for protein and other water-soluble hormones
 * If they are going to discuss animal and plant hormones, they should explain the difference between them
 * Therapeutic use is not as in depth as I expected it to be. I presume that if people wanted to know more information on the specific therapeutic uses for each hormone that they could go to the page for that specific hormone. I'm still learning what is expected of a page this general on Wikipedia
 * Hormone-behavior interactions and comparison with neurotransmitters sections do not have citations at all, so those would need some sources
 * The comparisons with neurotransmitters section, in my opinion, needs a lot of work because not only does it not have citations, but the bullet points seem a bit oversimplified. Use of sources could possibly make the comparisons more clear
 * I feel like an example of a binding protein and its respective hormone would benefit the binding protein section, as well as a list of known binding proteins and their respective hormones
 * The discovery section is practically nonexistent, does not give a date of discovery or who discovered it. It only provides a link to the first discovered hormone's Wikipedia page
 * I feel like a history section might also be beneficial to the article as a whole

Tone


 * Does not try to persuade audience
 * No real stance in subheadings
 * Professional and neutral tone overall

Citations


 * Some sources are questionable- for example, one is a website for a clinic
 * Citations are missing in some sections



Talk Page


 * One person on the talk page discussed that instead of going right into endocrine hormones (the most commonly understood hormones), to go into all types of hormones
 * After reading that, I realized that the article did not talk about the different categories of hormones at all, maybe just briefly in the first paragraph. Going more in depth on the different categories of hormones, like endocrine, paracrine, and autocrine, before delving into just endocrine hormones, might be extremely beneficial for the article


 * It seems as though everyone has ideas on how to fix the article but have yet to actually make those edits
 * The article itself is C-class and start-class and needs a lot of work
 * I feel like in class, we discussed the overview of hormones before going into depth, which allowed me to gain a greater understanding of the classes of hormones and types before understanding the functions of types of hormones and receptors

Article Selection Ideas


 * Hormone (Analysis is above)
 * Thymosin (talking about its role in cystic fibrosis, expanding on the pathway of the hormone, more of its role in diseases associated)

Notes:

Peptide hormones are made of a chain of amino acids that can range from hundreds to just 3, like prolactin.


 * Encoded in DNA
 * Can be modified by splicing or addition of carbohydrate chains
 * Hydrophilic
 * Packed in vesicles
 * Typically act on membrane receptors because of their inability to diffuse through the hydrophobic tails of the phospholipid bilayer

Amino acid and fatty acid hormones


 * Derived from an amino acid, most commonly tyrosine
 * Derived from fatty acid precursors
 * Act on membrane receptors
 * Stored in vesicles

Steroid hormones


 * derived from cholesterol
 * have 4 6-carbon rings
 * lipophillic (soluble in fats)
 * can cross the membrane, so can act on receptors in the nucleus or cytoplasm

(GET RID OF PLANT HORMONE SECTION AND ADD IT IN ONE SENTENCE TO ANOTHER SECTION)

History section notes


 * Berthold (1849)
 * Removed testes from a rooster
 * Smaller primary and secondary physical structures and no sexual behavior
 * Replaced testes in a different area of body
 * Normal physical anatomy and sexual behavior
 * Transplanted testes from a different rooster
 * Normal physical anatomy and sexual behavior
 * Significance
 * Location of the testes doesnt matter... something in the testes matters
 * Bayliss and Starling
 * Loewi