User:Lebrongoated/sandbox

Welcome to your sandbox!

Link to Project Resource Page
Project Homepage and Resources

Practice Editing Here (Nov 23rd in-class Wiki session work)

 * This is a place to practice clicking the "edit" button and practice adding references (via the citation button).
 * The name of my Wiki Article is "Penile Cancer".

Assignment # 3
Wikipedia Article Title: Penile Cancer

 Proposed Change:  I would like to update the ‘Diagnosis’ section of the article by adding a statement that says: “The International Society of Urological Pathology (ISUP) recommends the use of p16INK4A immunostaining for the diagnosis and classification of HPV-related penile cancer. ”

 Rationale for Proposed Change:  The diagnosis section of the article currently has no information on the tests used to confirm the presence of penile tumours in patients. It lists the various classifications and stages of penile cancer, but does not indicate how diagnoses are made in a clinical setting. I collected this information from the resource below :

Canete-Portillo, S., Velazquez, E. F., Kristiansen, G., Egevad, L., Grignon, D., Chaux, A., & Cubilla, A. L. (2020). Report From the International Society of Urological Pathology (ISUP) Consultation Conference on Molecular Pathology of Urogenital Cancers V: Recommendations on the Use of Immunohistochemical and Molecular Biomarkers in Penile Cancer. The American journal of surgical pathology, 44(7), e80–e86. https://doi.org/10.1097/PAS.0000000000001477

A point of controversy that may arise with my proposed change is that p16 immunostaining is used specifically for the diagnosis and classification of HPV-related tumours, while other methods are used for non-HPV-related cancers. I decided to move forward with this change because a large majority of penile cancers are HPV-related, making this information relevant to most penile cancer patients.

 Critique of Source:  One area of critique for the article comes from the survey that was held among the membership of the ISUP in order to determine penile cancer diagnosis techniques. A majority of survey respondents (60%) worked at an academic hospital where resources for immunohistochemical and molecular genetic analyses are likely much more accessible. This population of pathologists would be more likely to use p16 immunostaining for penile cancer diagnoses because these resources are readily available to them with a quick turnaround. Perhaps this presents a selection bias that may invalidate the results of the review article. However, this has not impacted my plans for the information I am choosing to share because I consulted other studies that confirmed this information. Additionally, survey respondents were 250 pathologists from 51 different countries, which improves the generalizability of the results.

What to post on the Wikipedia article talk page?

 * This will also be covered on Nov 23rd in class. Your group should use the below template to share an outline of your proposed improvements (including your new wording and citations). Article talk pages are not places to share your assignment answers. The Wikipedia community will be more interested in viewing your exact article improvement suggestions including where you plan to improve the article (which section), what wording you suggest, and the exact citation (Note: all citations must meet WP:MEDRS)
 * You will not be able to paste citations directly from your sandbox to talk pages (unless you are interested in editing/learning Wiki-code in the "source editing" mode). We suggest re-adding your citations on the talk page manually (using the cite button and populating the citation by pasting in the DOI, website, or PMID). You will have to repeat this process yet again when you edit the actual article live.
 * Talk Page Template: CARL Medical Editing Initiative/Fall 2020/Talk Page Template