User:LemonLimeHerbal/sandbox/Pat.rick.flower Peer Review

General info
LemonLimeHerbal
 * Whose work are you reviewing?


 * Link to draft you're reviewing:
 * Link to the current version of the article (if it exists):

Evaluate the drafted changes
Here is my peer review for your edit:

The edit created does not include adding a new lead that reflects new changes, however, the edit does focus on adding clarity to the meaning of conformational changes and how they affect whether or not an enzyme is functional or not. I find these additions extremely useful in giving the readers clarity on the interactions between the substrate and enzyme.

The content added is relevant to the article but it is more of a general statement towards all enzymes that interact with substrates. The information you contributed is from a reliable source but the source is dated since it was done in 2002, a more recent source would provide a stronger basis for the information.

Wonderful job keeping the content neutral and a great balance of information between binding site, conformational changes, and substrates on the enzyme. Maybe the flow of the article would be better if the edits were written before the information that mentions in detail the amino acids and their residues that are apart of the loops that block from substrate binding.

The content added did improve the quality of the overall article by talking about the mechanism of the loops that block the binding site. This information could assist readers who do not understand the topic more easily grasp the idea. Overall, I think this is a well-written and well-researched article. There could more improvements if there was a cartoon gif of the loops on the lactose synthase on how they open and close and see the parts that are affected by this mechanism.