User:Leslievazvalle29/sandbox

In a past experiment performed it was noted that counterions such primary amides under basic conditions were used to show the relationship between B and C forms of DNA. The overall shape and orientations of DNA is heavily dependent on its primary sequence and hydrogen bonding between its base pairs, which stabilizes and holds the confirmation of the double helices. C-DNA was shown to hold its confirmation without water and was able to form upon dehydration [1]. Some amides under basic conditions and low humidity showed to hold the C-form confirmation, but smoothly transitioned to B form DNA as the humidity was increased [1]. This may suggest a strong correlation between C-form and B-form DNA, which was also seen using Lithium salt at low humidity.