User:Lisalifepharm/sandbox

LifePharm Inc. is a privately held American company that manufactures grade nutritional supplements and skin care products for the health and wellness industry. Headquartered in Orange County, California, the company operates in 45 countries with offices located in the U.S.A., Europe, Russia, Indonesia, Malaysia, Philippines, South Korea and Japan. LifePharm was founded by CEO Wicky Suyanto, who is well versed in the nutritional supplement and skin care industry with more than 30 years of experience. Research and development on the company’s products is conducted by third party medical clinics, universities, and private laboratories. The scientific research team helps develop protocols for clinical and basic research studies to evaluate product ingredients and product formulas for safety and efficacy. Contents •	1History •	2Products o	2.1Nutritional Supplements o	2.2Skin Care •	3Business •	4External links •	5References LifePharm Type: Private Industry: Direct selling Founded: 2011 Founder: Wicky Suyanto Headquarters: Irvine, California United States Area served: International Key people: Wicky Suyanto (CEO) Products: Nutritional supplements, skin care Website: www.lifepharm.com History[edit] LifePharm Founder and CEO Wicky Suyanto grew up in Indonesia. In 1979, Wicky came to the United States to attend Pepperdine University and took an interest in alternative medicine, specifically nutritional supplements. He wanted to create a direct selling company that sold nutritional supplements, so those who sign up would have access to these nutritionals to improve their health, as well as the earning potential of a multi-billion-dollar industry. A LifePharm Independent Business Owner can purchase LifePharm Products at wholesale prices. They make a commission off the value assigned to each product or product pack as well as cash bonuses as defined in the LifePharm Compensation Plan. LifePharm launched in 2011 with one product: Laminine, a supplement that contains the proprietary  LifePharm Fertilized Avian Egg Extract, marine proteins and phyto proteins. Laminine was created based on research and studies dating back to 1929. John R. Davidson, a Canadian doctor, theorized that working with embryonic extracts derived from vertebrate animals might have factors that support healing or recovery mechanisms for utilizing in patients.14 Dr. Davidson was a pioneer in using vitamin therapy and embryonic extracts to support research in reversing certain disease processes in animal models and case report studies with patients he treated. He spent well over a decade developing and researching his theories.12,13,14 When Dr. Davidson passed away in 1943, his research on fertilized avian eggs was not carried on to future generations and was soon forgotten. Nearly 50 years later, the pursuit of fertilized avian egg extract was revived by Norway’s foremost expert on fertilized egg research: Dr. Bjoedne Eskeland.15 He took Dr. Davidson’s original research a step further. and hypothesized that fertilized avian eggs contained a special combination of peptides and protein biofactors  that could support cellular regeneration and tissue repair beneficial to supporting health. More than 80 years later, Dr. Davidson’s initial discovery is what lead to the formulation of Laminine. The Laminine formula contains the proprietary LifePharm fertilized avian egg extract, along with a blend of marine and phyto proteins. The three ingredients together provide 22 amino acids essential for cellular health. Company Milestones •	June 2011 - LifePharm opens its doors in Orange County, California. •	July 2012 - The LifePharm flagship product, Laminine is featured on the American Health Journal. •	November 2013 - LifePharm launches second product, OMEGA+++ at global convention. •	December 2013 - August 2014 - LifePharm opens for direct shipment in Canada, Australia, New Zealand, Latvia and Lithuania. •	November 2014 - LifePharm launches DIGESTIVE+++ and IMMUNE+++. •	December 2014 - LifePharm presents Laminine at the 22nd Annual World Congress of the American Academy of Anti-Aging Medicine. •	January 2015 - The LifePharm flagship product, Laminine is published for the first time in the 2015 Physicians’ Desk Reference. This publishing continues in the 2016, 2017 and 2018 editions. •	November 2016 – Laminine and IMMUNE+++ are published in the Journal of the American College of Nutrition •	2017 – Laminine is published in the Orthopedic and Muscular System Current Research •	February 2017 - LifePharm launches its first skin care product, Lamiderm Apex. •	June 2017 – Proprietary LifePharm Egg Extract is published in Clinical and Experimental Dermatology •	July 2017 – Laminine is published in the 18th European Diabetes Congress •	October 2017 - LifePharm presents Laminine at the 7th International Conference on Predictive, Preventative and Personalized Medicine & Molecular Diagnostics, Chicago. •	October 2018 – Lamiderm Apex is published by the 14th Coastal Dermatology Symposium by Global Academy of Medical Education •	November 2018 – Laminine and DIGESTIVE+++ are Published in the Journal of the American College of Nutrition •	February 2019 – LifePharm launches REFIVE, a packet containing 2 LAMININE, 1 OMEGA+++, 1 DIGESTIVE+++ and 1 IMMUNE+++. •	July 2019 – LifePharm launches its first skin nutrition supplement, OMNIA. •	August 2019 – LifePharm launches in Japan As of 2019, LifePharm has over 500,000 Independent Business Owners. IBOs have earned over $1,000,000,000.00 from 2011 to 2019. Products[edit] Nutritional Supplements[edit] The first LifePharm supplement Laminine, contains a compound that is essential in supporting embryonic development. This compound is called Fibroblast Growth Factor 2 (FGF2). Research shows that FGF2 plays an important role in proliferation, differentiation, and survival of cells of almost all organ systems by regulating the activity of multiple genes.16 Over the last several decades, fibroblast growth factors and their receptors have shown to be highly involved in both embryonic development and tissue repair. Many studies point to somatic stem cells as primary targets of FGF signaling in both tissue homeostasis and repair.17 FGFs appear to promote self-renewing proliferation and inhibit cellular senescence in nearly all tissues tested including stem cell self-renewal.17 In addition to Laminine, LifePharm manufactures three other health supplements: OMEGA+++ focuses on circulatory health; DIGESTIVE+++ targets digestive health; and IMMUNE+++ concentrates on strengthening the immune system.; and OMNIA supports skin, hair and nail health. Skin Care[edit] LifePharm manufactures Lamiderm Apex, a skin rejuvenation serum that supports healthy skin. This serum contains the proprietary LifePharm Fertilized Avian Egg Extract.

Laminine and Telomerase Enzyme Activity In normal proliferating human cells, telomeres at the end of chromosomes are shortened at every cell division unless the cells express telomerase (the enzyme that lengthens telomeres).17 When telomeres become too short, the genomic stability is altered and a DNA-damage response is induced.17 It is theorized that telomere shortening is responsible for both somatic and stem cell aging and eventual senescence or cell death. It is therefore hypothesized that if telomerase can be stimulated to repair and lengthen telomeres then cell regeneration can ensue to continue to reproduce healthy cells.17 LifePharm scientists initiated a clinical study to determine if Laminine supports increased telomerase activity leading to more stable cell division in both somatic and stem cells. As stem cells are thought to sustain tissue growth, homeostasis and repair throughout the lifetime, observing enhanced telomerase activity would be an indicator that the regenerative potential of tissues was partially restored delaying senescence and thus cell aging.17 Dr. Rafael Gonzalez PhD observed subjects who consumed four Laminine daily for 90 days. The subjects who took Laminine did not change their diets or lifestyle habits, but still showed evidence of telomere lengthening. The study revealed that consuming Laminine supports telomerase activity that results in longer telomeres for improved health.10 Business[edit] LifePharm does not use retail channels to distribute its products. The products are distributed throughout the United States and in 45 countries around the world through a network of Independent Business Owners (IBOs). External links[edit] •	LifePharm Inc Official website •	Lamiderm Apex Official website References[edit] 1.	Jump up ^ LifePharm (1 Jan 2011). "LifePharm Global Network -LinkedIn". LifePharm. Retrieved 11 Jan 2017. 2.	Jump up ^ LifePharm (1 Jan 2011). "LifePharm - Countries and Languages". LifePharm. Retrieved 11 Jan 2017. 3.	Jump up ^ LifePharm (1 Jan 2011). "LifePharm - Corporate Headquarters and Global Offices". LifePharm. Retrieved 11 Jan 2017. 4.	Jump up ^ LifePharm (1 Jan 2011). "LifePharm - Meet LifePharm Executive Team". LifePharm. Retrieved 11 Jan 2017. 5.	Jump up ^ LifePharm (1 Jan 2011). "LifePharm - Meet LifePharm Scientific Advisory Board". LifePharm. Retrieved 11 Jan 2017. 6.	Jump up ^ LifePharm (1 Jan 2011). "LifePharm - Meet LifePharm Scientific Advisory Board". LifePharm. Retrieved 11 Jan 2017. 7.	Jump up ^ Coutu DL, Galipeau J. (1 Jan 2015). "Roles of FGF signaling in stem cell self-renewal, senescence and aging". nih.gov. Retrieved 11 Jan 2017. 8.	Jump up ^ LifePharm (1 Jan 2011). "LifePharm". LifePharm. Retrieved 11 Jan 2017. 9.	Jump up ^ LifePharm (1 Jan 2017). "Lamiderm Apex - Official Website". LifePharm. Retrieved 11 Jan 2017. 10.	^ Jump up to: a b c Physicians' Desk Reference (1 Jan 2011). "Laminine (fertilized avian egg extract/marine protein/phyto protein) - Full Prescribing Information". PDR.net. Retrieved 11 Jan2017. 11.	The Laminine and Telomere Connection 2017. Da Vinci Laboratories in Loma Linda, California. Rafael Gonzalez, PhD. 12. J.R. Davidson, An Attempt to Inhibit the Development of Tar-Carcinoma in Mice (Fourth Report), The Effects of Vitamins on the Tumour Threshold, The Canadian Medical Association Journal, Volume 38, No. 6, June 1938. 13.	J.R. Davidson, A Case of Adolescent Myxoedema Accompanied by Nephrosis and in by Tetany of Parathyroid Origin, Treated with Thyroid and Collip’s Parathyroid Extract, The Canadian Medical Association Journal, July 1925. 14.	J.R. Davidson, An Attempt to Inhibit the Development of Tar-carcinoma in Mice (Fifth Report), The Canadian Medical Association Journal, Volume 41, No.3, September 1939, Page 223-225. 15.	Eskeland B. Thom E. Svendsen KO. Sexual desire in men: effects of oral ingestion of a product derived from fertilized eggs. J Int Med Res. 1997;25:62–70. 16.	D.L. Coutu, J. Galipeau, Roles of FGF Signaling in Stem Cell Self-Renewal, Senescence and Aging. AGING, October 2011 Vol. 3, No. 12, Page 920-933. 17.	Chen CH, Poucher SM, Lu J, Henry PD. Fibroblast growth factor 2: from laboratory evidence to clinical application. Curr Vasc Pharmacol. 2004 Jan;2(1):33-43.