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The queen bee acid (10-hydroxy-2-decenoic acid) or 10-HDA is a bio-active compound found in royal jelly.

Royal jelly is created in the hypopharyngeal and mandibular glands of the female worker bees' heads in order to feed the prospective queen larvae as well as feeding the queen herself.

Royal jelly acid is being investigated for its pharmacological activities. Reports indicate that it promotes neurogenesis of neural stem/progenitor cells (cells capable of differentiating into neurons, astrocytes, or oligodendrocytes) in vitro and could provide an effective method to treat and prevent neurological disorders.

In addition, royal jelly acid has been reported to have anti-tumor, anti-biotic, immunomodulatory, estrogenic, neurogenic, and innate immune response modulating activities.

In the United States, the Food and Drug Administration has taken legal action against companies that have used unfounded claims of health benefits to market royal jelly products.

Products from bees are considered to be a great source of nullifying the effects of oxidative stress underlying the pathogenesis of many diseases. In diseases such as Parkinson's disease, the application of β-amyrin can aid in therapy.