User:Lkazmierczak1/sandbox

Week 2 Assignment: Article Critique
The article Physiology seems to be well constructed overall. However, there are a few issues that need to be addressed. The third paragraph of the introduction is not cohesive and contains two ideas that belong in separate paragraphs. Furthermore, certain parts of Women in Physiology are either biased or need citations. For example, the author notes that Ida Hyde was a large proponent of gender equality in all scientific fields. The claim regarding her avocation for gender equality in all scientific fields promotes the scientist's image and needs proper attribution to a source.

Week 4: New Sources, Ideas, and Notes for Improvement
Existing resources:

[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852998/ Neely, K. A., & Gardner, T. W. (1998). Ocular neovascularization: clarifying complex interactions. The American journal of pathology, 153(3), 665-670.]

[http://www.sciencedirect.com/science/article/pii/S0142961206004716 Rücker, M., Laschke, M. W., Junker, D., Carvalho, C., Schramm, A., Mülhaupt, R., ... & Menger, M. D. (2006). Angiogenic and inflammatory response to biodegradable scaffolds in dorsal skinfold chambers of mice. Biomaterials, 27(29), 5027-5038.]

New Resources:

[http://www.sciencedirect.com/science/article/pii/S0039625798000356 Lee, P., Wang, C. C., & Adamis, A. P. (1998). Ocular neovascularization: an epidemiologic review. Survey of ophthalmology, 43(3), 245-269.]

* currently unable to find medical textbooks online or find encyclopedias with a general overview of neovascualrization

Notes re: current version

-Growth factors that inhibit neovascularization should not be in the lead section. It needs to be transferred to a subsection, possibly under treatment or etiology. -There should be a separate section devoted to neovascularization in ophthalmology.

-Possible Outline: -Lead (Overview including definition) -Neovascularization in ophthalmology -different types -causes -manifestions -treatment -prognosis -current research -Other types of neovascularization -types -causes -manifestions -treatment -prognosis -current research

Week 5: Editing the lead
"Neovascularization is the natural formation of new blood vessels (neo- + vascular + -ization), usually in the form of functional microvascular networks, capable of perfusion by red blood cells, that form to serve as collateral circulation in response to local poor perfusion or ischemia. Neovascularization is conventionally distinguished from angiogenesis in that angiogenesis is mainly characterized by the protrusion and outgrowth of capillary buds and sprouts from pre-existing blood vessels. Vasculogenesis can be synonymous with neovascularization but also often has reference instead to prenatal development and the initial embryologic formation of blood vessels. 'Growth factors that inhibit neovascularization include those that affect endothelial cell division and differentiation. These growth factors often act in a paracrine or autocrine fashion; they include fibroblast growth factor, placental growth factor, insulin-like growth factor, hepatocyte growth factor, and platelet-derived endothelial growth factor." (Part that is bold/italicized belongs under a seperate section? Too detailed for lead?)'

'"In ophthalmology, choroidal neovascularization is the formation of a microvasculature within the innermost layer of the choroid of the eye. Neovascularization in the eye can cause a type of glaucoma (neovascularization glaucoma) if the new blood vessels' bulk blocks the constant outflow of aqueous humour from inside the eye." (I will edit this to go under an opthalmology subsection)'