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Cdc14 and Cdc14 are a gene and its protein product respectively. Cdc14 is found in most of the eukaryotes.

Hartwell LH, Culotti J, Pringle JR, Reid BJ (1974) Genetic control of the cell division cycle in yeast. Science 183:46-51

Cdc14 is also involved in meiosis in budding yeast. Cdc55, a regulatory subunit of Protein phosphatase 2 (PP2A), sequesters Cdc14 in the nucleolus during early stage of meiosis. The sequestration of Cdc14 is necessary for assembling the meiosis I spindle. Although, the early stage sequestration of Cdc14 is not essential for separation of chromosomes. FEAR (Cdc Fourteen Early Anaphase Release) complex proteins, SLK19 and SPO12 regulate the release of Cdc14. The release of Cdc14 from nucleolus results in cdk1 inactivation and ultimately in disassembly of spindle during Anaphase of meiosis I. Cells deprived of Cdc14 or SLK19 and SPO12 have abnormal meiosis. They have only one division during meiosis. The chromosomes also segregate abnormally. The abnormality arises due to delay in dissembling of spindle during Anaphase I. However, the segregation of chromosomes continue and both the phases of meiotic segregations take place on prolonged meiosis I spindle. Cdc14 along with SPO12 and SLK19 play a critical role in ensuring that the two phases of chromosomal segregation take place consecutively during meiosis.

Bizzari F, Marston AL (2011) Cdc55 coordinates spindle assembly and chromosome disjunction during meiosis. The Journal of cell biology, 193:1213-1228.

Marston AL, Lee BH, Amon A (2003) The Cdc14 phosphatase and the FEAR network control meiotic spindle disassembly and chromosome segregation. Developmental cell, 4:711-26.

Buonomo SB, Rabitsch KP, Fuchs J, Gruber S, Sullivan M, Uhlmann F, Petronczki M, Tóth A, Nasmyth K (2003) Division of the nucleolus and its release of CDC14 during anaphase of meiosis I depends on separase, SPO12, and SLK19. Developmental cell, 4:727-39.