User:Llivermore/sandbox

Dennis Leston, (2 February 1917 – 7 October 1981) was an English entomologist best known for his contributions to the study of Heteroptera.

Prior to his academic work Leston served with the Royal Army Medical Corps during World War II where he developed his fascination with insects.

Leston was a member of the South London Entomological Society and was elected a Fellow of the Royal Entomological Society in 1949. After gaining a D.I.C. by research from Imperial College in the early 1960s Leston studied and worked at a number of universities, including the University of Ghana.

Category:Fellows of the Royal Entomological Society

Jean Péricart was a French entomologist.

His notable work on Hemiptera covered the families Anthocoridae, Saldidae, Tingidae, Berytidae and Rhyparochromidae.

Distribution
The earliest collected specimens with a known locality are those of Goeze from France as the specimens described by Linnaeus have no stated or surviving locality data. The current distribution is extensive and covers: Europe, from Portual to Finland; Asia, from Russia to China; and Africa, known only from Algeria.

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2-Aminobenzamide is a benzamide. It is light brown to grey-brown either as a powder or flakes and has the chemical formula C{{sub|7}}H{{sub|8}}N{{sub|2}}O.

Uses
It is known since 1980 that 3-Aminobenzamide is an inhibitor of poly ADP ribose polymerase (PARP), an enzyme responsible for DNA repair, transcription control, and programmed cell death. When PARP is activated it rapidly uses up stores of NAD+ in the cell as it performs DNA repair. Low levels of NAD+ deplete the amount of ATP found in the cell which can lead to cell death. The structure of 3-aminobenzamide is similar to that of NAD+ so it binds to PARP and prevents it from using up NAD+. PARP is often a target of cancer therapy and so 3-Aminobenzamide could potentially be used as an anticancer drug.