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But, according to the latest research, other factors, not directly related to caloric intake, can also contribute to obesity.

In an article by Danielle Moores, it is concluded that there are many contributing factors to obesity which are not tied to overeating or a sedentary lifestyle::


 * a diet that lacks nutritional value
 * disrupting hormonal balance by not allowing the body to sleep an adequate number of hours
 * genetics
 * natural aging
 * the inability to lose weight following a pregnancy
 * medical conditions, such as: polycystic ovary syndrome, Prader-Willi syndrome, Cushing syndrome, hypothyroidism (underactive thyroid); and osteoarthritis
 * medications

In addition, some research suggests the following as contributors to obesity:


 * air conditioning
 * one's ability to delay gratification
 * the thickness of the prefrontal cortex of the brain

Dr. Jose Ordovas, senior author and director of Nutrition and Genomics, states, "Obesity is not simply a result of food intake alone." As of 2016 it had become clear that there may be a genetic component to obesity, and scientists now have the data to prove it.

Genetics

A correlation between obesity and genetics has been proven. In August 2018, Chao-Qiang Lai and his international research team discovered that the presence of the human gene, APOA2, could result in a higher BMI in individuals. Chao-Qiang is a molecular biologist from Agricultural Research Service’s (ARS) Nutrition and Genomics Laboratory at Tufts University, Boston. His study researched the role of the gene as it related to the individual's diet. Specifically, how including high levels of saturated fat in the individual's diet was tolerated by those individuals having the greatest epigenetic marker near the APOA2 gene. They determined that individuals who consumed a diet high in saturated fats, who carried the APOA2 genetic factor, would gain more weight than those individuals who also consumed a diet high in saturated fats, but did not carry the genetic factor.

Only for reference:

Air Conditioning

Obesity in the US is generally caused by long term patterns of behavior that including sitting still and not exercising enough, eating too much, and consuming too much high calorie food and drinks.

As of 2016 it had become clear that there may be a genetic component to obesity, but relatively little was known about how genes might influence weight change over time.

https://www.sciencedaily.com/releases/2018/08/180828172040.htm

Article ONE to review:

McGill University. "The link between obesity, the brain, and genetics: When it comes to weight gain, the problem may be mostly in our heads, and our genes." ScienceDaily. ScienceDaily, 28 August 2018. .

McGill University. (2018, August 28). The link between obesity, the brain, and genetics: When it comes to weight gain, the problem may be mostly in our heads, and our genes. ScienceDaily. Retrieved September 17, 2018 from www.sciencedaily.com/releases/2018/08/180828172040.htm

McGill University. "The link between obesity, the brain, and genetics: When it comes to weight gain, the problem may be mostly in our heads, and our genes." ScienceDaily. www.sciencedaily.com/releases/2018/08/180828172040.htm (accessed September 17, 2018).

Uku Vainik, Travis E. Baker, Mahsa Dadar, Yashar Zeighami, Andréanne Michaud, Yu Zhang, José C. García Alanis, Bratislav Misic, D. Louis Collins, Alain Dagher. Neurobehavioral correlates of obesity are largely heritable. Proceedings of the National Academy of Sciences, 2018; 201718206 DOI: 10.1073/pnas.1718206115

Article TWO to review:

https://www.ars.usda.gov/news-events/news/research-news/2018/international-research-team-finds-correlation-between-genetics-and-obesity-is-modified-by-diet/

In August 2018, Chao-Qiang Lai and his research team discovered that the presence of the human gene, APOA2, could result in a higher BMI in individuals.[1] Chao-Qiang is a molecular biologist from Agricultural Research Service’s (ARS) Nutrition and Genomics Laboratory at Tufts University, Boston.[1] His study researched the role of the gene as it related to the individual's diet.. Specifically, how the inclusion of saturated fat in the individual's diet was tolerated as identified by what the epigentic marker for

Article on Air Conditioning (Ambient Temperature)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975627/

Article on 10 NEW reasons for obesity

https://www.cbsnews.com/news/study-suggests-10-new-obesity-causes/

SOURCE: Keith, S.W. "International Journal of Obesity," advance online publication, June 27, 2006.

By Daniel J. DeNoon

Reviewed by Louise Chang, MD

© 2006, WebMD Inc. All rights reserved

© 2006 WebMD, LLC.. All Rights Reserved.

Article on 3 REAL Contributors to the Obesity epidemics

https://www.huffingtonpost.com/lorie-eber/the-3-real-causes-of-obes_b_7004668.html

https://www.healthline.com/health/obesity#prevention


 * Adult obesity facts. (2018). cdc.gov/obesity/data/adult.html
 * Body mass index: Considerations for practitioners. (n.d.). cdc.gov/obesity/downloads/bmiforpactitioners.pdf
 * Child obesity facts: Prevalence of childhood obesity in the United States. (2018). cdc.gov/obesity/data/childhood.html
 * Facts and statistics: Physical activity. (2017). https://www.hhs.gov/fitness/resource-center/facts-and-statistics/index.html
 * F as in fat: How obesity threatens American’s children. (n.d.). https://www.rwjf.org/content/dam/farm/reports/reports/2010/rwjf62003
 * Guo X, et al. (2017). High fat diet alters gut microbiota and the expression of paneth cell-antimicrobial peptides preceding changes of circulating inflammatory cytokines. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339499/
 * Hall KD, et al. (2016). Calorie for calorie, dietary fat restriction results in more body fat loss than carbohydrate restriction in people with obesity. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603544/
 * Mayo Clinic Staff. (2015). Obesity. mayoclinic.org/diseases-conditions/obesity/symptoms-causes/syc-20375742
 * Mayo Clinic Staff. (2018). Cushing’s syndrome. mayoclinic.org/diseases-conditions/cushing-syndrome/symptoms-causes/syc-20351310
 * Mayo Clinic Staff. (2018). Hypothyroidism (underactive thyroid). mayoclinic.org/diseases-conditions/hypothyroidism/symptoms-causes/syc-20350284
 * Mayo Clinic Staff. (2018). Prader-Willi syndrome. mayoclinic.org/diseases-conditions/prader-willi-syndrome/symptoms-causes/syc-20355997
 * Obesity. (n.d.). endocrinefacts.org/health-conditions/obesity/
 * O’Neill AM. (2016). High-fat Western diet-induced obesity contributes to increased tumor growth in mouse models of human colon cancer. https://www.ncbi.nlm.nih.gov/pubmed/27866828
 * Polycystic ovary syndrome. (n.d.). ncbi.nlm.nih.gov/pubmedhealth/PMHT0024506/
 * Position of the American Dietetic Association: Fat replacers. (2005). https://jandonline.org/article/S0002-8223(04)01853-X/fulltext