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Cholesteryl ester is found in human brains as lipid droplets which stores and transports cholesterol. ( https://www.nature.com/articles/s41598-020-76973-8 ).

Increased levels of cholesteryl ester has been found in certain parts of the brain of people with Huntington disease. Higher concentrations of cholesteryl ester has been found in the caudate and putamen but not the cerebellum of people with Huntington Disease compared to that of controls. ( https://go-gale-com.proxy.wexler.hunter.cuny.edu/ps/i.do?p=AONE&u=cuny_hunter&id=GALE|A643924682&v=2.1&it=r )

Increase in cholesteryl ester has also been found in other neurological disorders like multiple sclerosis and Alzheimer’s disease ( https://www.nature.com/articles/s41598-020-76973-8 ).