User:LutyeusMaximus/sandbox

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GA-Rated Article
Just below professional encyclopedia quality. The information is clear with no obvious problems and useful to all readers
 * Well-Written
 * Clear
 * Concise
 * Respects Copyright Laws
 * No Spelling or Grammar Mistakes
 * Complies with manual of style guidelines
 * Verifiable
 * Full list of references
 * In-line citations are used
 * No original research is used
 * Broad
 * Covers main topic without going into erroneous detail
 * Neutral
 * Covers all viewpoints without bias
 * Stable
 * Article doesn't change daily due to an edit war
 * Illustrated
 * Appropriate images are used, including tagged copyright status and fair use rationales

B-Rated Article
Leaves room for content to be expanded, but reader is satisfied and not left wanting more
 * Reasonably Well-Written
 * No major spelling or grammar mistakes
 * May need work on flow
 * Referenced
 * In-line citations
 * May not use citation templates or ref tags correctly
 * Covers Topic
 * Covers the meat of the material on the subject, but may need expansion in certain areas
 * Understandable
 * Written for a broad audience, may still need to expand upon some of the technical background of the article
 * Defined Structure
 * Content is organized into reasonable and understandable groups
 * Contains Supporting Materials
 * Includes images, diagrams or infoboxes

Prevalence of Kidney Stones in the United States
Kidney stones (nephrolithiasis or urolithiasis) affect about 1 and 11 people in the United States, this is an increase in stone disease when compared to the NHANES III cohort from 1988-1994, which previously measured stones as affecting 1 in 20 people in the United States. This increase in stone burden has many implications as the disease affects mostly working-age people, however an increase in pediatric patients has also been noted. It was also noted that an increase of incidence was seen in all demographic cohorts; age, gender & racial/ethnic groups. This increase in incidence is most likely not attributed to one factor, most likely it is a multitude of factors, with diet being one of the central factors.

Urolithiasis and the Risk of ESRD
With an increase in the prevalence of Kidney Stones in the United States to 1 in 11 there is increased concern about whether those who suffer from kidney stones are at increased risk for End Stage Renal Disease (ESRD). In a large cohort consisting of 6926 stone formers and 24620 matched controls from 1984 to 2008, researchers were able to determine that symptomatic kidney stone formers are indeed at an increased risk for ESRD independent of several other cardiovascular risk factors.

Comments for Histone Octamer
Hi Rokas1 & Demille96, So far your article has a good start. Here are a few things I noticed that I think you could do easily to help move your article along:
 * the very first sentence which defines octamer with the word octamer is a little redundant and some of the grammar in the sentence needs improvement.
 * add citations in first paragraph
 * I know the article isn't big yet but I would add a contents box at the top of the page, this seems to be general wikipedia format and as your article expands I think it will help you keep things organized
 * I would remove top banner about citations since you guys are starting to add them now
 * In the first paragraph you jump right into the structure of histone octamers. I think this could be a sub-section.  I think in the first paragraph readers are just looking for some information on general function and maybe location of histone octamers
 * the sentence in the first paragraph about histone formation in vivo, is a little confusing. It took me a couple reads to figure out what is trying to be said.
 * I think the second section about histone octamer research really has more information on the history of histone ocatmers and their structure.
 * the first sentence of the second section about post-translational modifications is the start to an entirely separate section I think for later in the article.
 * I updated one of your sources which had a few spaces missing between words

I hope you don't think I was too nit-picky but I think you have a good start to your article! LutyeusMaximus (talk) 23:43, 30 October 2013 (UTC)