User:LuzAreliContreras/Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. Androgen receptor

Research has shown the effects of androgen receptors in prostate cancer pathway by irregular regulation of coregulators.

In men, a high expression in AR has been linked to aggression and sex drive by affecting the HPA and HPG axis.