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The Joint Research Center for Computational Biomedicine (JRC-COMBINE) in Aachen, Germany is a joint venture between RWTH Aachen University, University Hospital Aachen, and Bayer AG aiming to close the gap between academic and industrial research.

The Center
Computational Biomedicine is a key technology en route to better healthcare, agriculture and biotechnology. In particular, computational models linking bench and bedside are essential for the development of safe, efficient, and personalized therapies of complex diseases. To realize the full potential of computational biomedicine, these models must address the real complexity of medicine, integrating mechanistic modeling with big data analysis.

The newly established interdisciplinary Joint Research Center for Computational Biomedicine (JRC-COMBINE) in Aachen, Germany combines advanced modelling technologies and systems biology approaches with expertise from industry and academia to provide tangible benefit for clinics, industry and society at large.

Research Focus:
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Selected Publication

 * Brehme, M. et al.: A conserved chaperome sub-network safeguards protein homeostasis in aging and neurodegenerative disease. Cell Reports. 2014; 9:1135–1150,.