User:Maferhuicom/sandbox

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Practice Editing Here (Nov 23rd in-class Wiki session work)

 * This is a place to practice clicking the "edit" button and practice adding references (via the citation button).
 * This is my article: Chronic lymphocytic leukemia. The reference that I am using for by changes is being used as a citation for this sentence.

Assignment # 3

 * Note: You will be emailing your assignment # 3 directly to your tutor, however, please paste a version here that excludes your personal information. This will allow us to support your efforts on Wikipedia prior to editing "live" in the article.
 * Assignment 3 submission: I propose to change the sentence "Some relevant genetic mutations may be inherited; in around 9% of CLL cases a parent had CLL." in the Causes section for the following three sentences: Some relevant genetic mutations may be inherited. Since there is no one single mutation that causes CLL in all cases, an individual’s susceptibility may be impacted when multiple mutations that increase the risk of CLL are co-inherited. Up until 2014, very few of these mutations or significant “risk alleles” had been identified.
 * Rationale: The original Wikipedia article said: “Some relevant genetic mutations may be inherited; in around 9% of CLL cases a parent had CLL”. This sentence was not cited, and if it had been, it could have easily been from a primary study looking at the odds of patients with CLL having parents with CLL. I think that this statement could make people with CLL worry about potentially giving their children CLL. The sentence also does not make it clear that a combination of mutation would need to be inherited in order to increase the risk of CLL on the child.   I believe that my changes portray a more accurate picture of what the current knowledge is in terms of inherited mutations in CLL. I wanted to especially highlight the fact that only a few risk alleles for CLL have been identified, and that more information on the topic is needed.
 * No area of controversy or dissenting opinions on the topic were identified.
 * Critique of source: There seems to be little research on the topic, so unfortunately the most up to date secondary source is from 2014. Nevertheless, the systematic review came from a reputable journal (“leukemia and lymphoma”), it did not seem biased, and the authors made a good analysis of the internal validity of their review and of the articles included in the review.

What to post on the Wikipedia article talk page?

 * This will also be covered on Nov 23rd in class. Your group should use the below template to share an outline of your proposed improvements (including your new wording and citations). Article talk pages are not places to share your assignment answers. The Wikipedia community will be more interested in viewing your exact article improvement suggestions including where you plan to improve the article (which section), what wording you suggest, and the exact citation (Note: all citations must meet WP:MEDRS)
 * You will not be able to paste citations directly from your sandbox to talk pages (unless you are interested in editing/learning Wiki-code in the "source editing" mode). We suggest re-adding your citations on the talk page manually (using the cite button and populating the citation by pasting in the DOI, website, or PMID). You will have to repeat this process yet again when you edit the actual article live.
 * Talk Page Template: CARL Medical Editing Initiative/Fall 2020/Talk Page Template