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Resident Evil, known in Japan as Biohazard, is a survival horror media franchise created by Shinji Mikami and Tokuro Fujiwara, and owned by the Japanese video game company Capcom. The franchise focuses on a series of survival horror games and incorporates live-action films, animations, comic books, novels, audio dramas, and merchandise. The story follows outbreaks of zombies and other monsters created mainly by the Umbrella Corporation.

The first Resident Evil was released in 1996, taking place in a mansion overrun with zombies. The franchise has grown to encompass numerous sequels of various genres, incorporating elements of action, exploration, and puzzle solving, and storylines inspired by horror and action films.

Most of the games in the series have been positively received and commercially successful. As of 2018, the Resident Evil series has shipped more than 82 million copies worldwide, making it one of the best-selling video game franchises of all time.

Main series
1996's Resident Evil for the PlayStation follows protagonists Chris Redfield and Jill Valentine, who become trapped in a mansion in the mountains, trying to search for the survivors of the Bravo team of the special police unit S.T.A.R.S. They discover that the mansion conceals the Umbrella Corporation's base where they developed the T-Virus with their end-goal being the creation of a bio-weapon known as the Tyrant (for whom the virus named). Playing as either of the characters, the player must navigate the mansion alternately with the help of Barry Burton or Rebecca Chambers, until they are betrayed by Albert Wesker who was secretly planning to steal the T-Virus. Though appearing to be killed by the Tyrant, Wesker survived and masterminded some later events behind the scenes.

Resident Evil Zero, a prequel released originally for the GameCube, details the events leading up to the first game and follows Rebecca Chambers as she is separated from the Bravo team and has to team up with a fugitive Billy Coen.

Resident Evil 2 follows a few months after the events of the first game when rats start infecting the population of Raccoon City with the T-Virus. Playing alternately as Claire Redfield, the sister of Chris from the first game, or Leon Kennedy, a rookie police officer starting on the day of the outbreak. The players must find and escape from the city while at the same time confronting the mad scientist William Birkin.

Resident Evil 3: Nemesis, set both before and after the events of the second game, follows Jill Valentine's escape from Raccoon City while being pursued by another Umbrella bio-weapon, the Nemesis-T Type. The plot concludes with the sterilization of Raccoon City by a nuclear strike.

Resident Evil: Code Veronica follows Claire's journey after escaping Raccoon City. She is captured trying to break into Umbrella's Paris facility and transported to one of their research facilities. The facility is attacked by Albert Wesker's forces and becomes also over-run with T-Virus. Claire escapes and starts looking for her brother Chris, while having to deal with Alfred and Alexia Ashford. Unbeknownst to her, Chris finds his way to the island and tracks Claire to the Arctic Umbrella facility. At the game's finale, Chris defeats the genetically-modified Alexia, faces off against Wesker and escapes with Claire.

Resident Evil 4 follows Leon Kennedy's mission to rescue the daughter of the president of the United States, who has been captured by a Spanish Cult led by Osmund Saddler, the Illuminados. Instead of T-Virus infected zombies, Leon faces off against villagers infected with the Las Plagas parasite, which makes them unyieldingly murderous but also maintains their dexterity and mobility, unlike the slow, shambling undead.

Resident Evil 5 concerns Chris Redfield's attempts to stop the selling of illegal bio-weapons in Africa, helped by Sheva Alomar. The plot eventually involves Albert Wesker's plans to destroy humanity with a Las Plagas type parasitic life-form called Uroboros.

Resident Evil 6 follows multiple protagonists, including Leon Kennedy, Chris Redfield, Ada Wong and Jake Muller, who become involved in a terrorist strike using bio-weapons which results in the zombification of the President of the United States. The story involves a new fast-acting zombie virus called the C-Virus which has been weaponised by the NSA to induce fear in the general populace and the individual characters' attempts to stop it from spreading.

Resident Evil 7: Biohazard puts players into the shoes of an ordinary man named Ethan Winters who wants to locate his missing wife, Mia, and he has to defend himself against a strange family inside their seemingly abandoned house. The game is the first main entry to be entirely shown in a first person view which is new to the primary series (although some of the previous spin off games utilized this viewpoint) and unlike the recent sequels, the game focuses more on what survival horror gaming was like prior to the action style route undertaken after Resident Evil 4 and similar games, by having the player having to evade the enemies more often, but there are still boss battles and puzzles to solve. Later, Capcom unveiled downloadable content chapters, Not a Hero, which focuses on fast-paced action, with the returning Chris Redfield, and End of Zoe, with a more horror tone which focuses on the ill-fated, Zoe Baker.