User:MartinHabib1/Dissociation rate

Direct measurements using electrospray ionization mass spectrometry (ESI-MS) have quantified dissociation rate constants for high-affinity ligand-protein interactions, such as the biotin-streptavidin system, offering a deeper understanding of enzyme-substrate dynamics. Recent computational studies have provided insights into the diffusional processes that influence the dissociation rates of biomolecular complexes, highlighting the importance of molecular movement and binding specificity in these interactions, the importance is considering both the physical movement of molecules and their binding specificities when analyzing dissociation rates.