User:MatthewMiller71/Cerebral Arteriosclerosis

Cerebral Arteriosclerosis is the build-up of plaque in the blood vessels of the brain. Some of the main components of plaque are connective tissue extracellular matrix, including collagen, proteoglycans, fibronectin, and elastic fibers; crystalline cholesterol, cholesteryl esters, and phospholipids; cells such as monocyte derived macrophages, T-lymphocytes, and smooth muscle cells. The plaque that builds up can lead to other problems such as stroke, because the plaque disrupts blood flow within the intracranial artery. This causes the downstream sections of the brain that would normally be supplied by the blocked artery to suffer from ischemia.