User:Matthomas118/NOREPINEPHRINE TRANSPORTER

Norepinephrine Transporter (NET)

Brief introduction

Function

 * norepinenphrine

NET SNPs

 * briefly- what SNPs are and why nonsynonymous SNPs are areas of interest for researchers
 * evidence suggesting relationship between SNPs and disorders such as ADHD and depression
 * only established relationship is between missense (nonsynonymous) polymorphism Ala457Pro and orthostatic intolerance (source: Tellioglu) [see below for OI]
 * table of some SNPs (GoogleBooks- Reith)

Clinical Significance

 * research with ADHD and depression etc. has yielded evidence but nothing has been proven yet (source: Tellioglu)

Orthostatic Intolerance

 * SNP Ala457Pro

Norepinephrine reuptake inhibitor

 * briefly, what it is and how it affects the NET, then below name medications for each condition

Further Research

 * Understanding mental illness

Division of Workload
We have decided to divide the research into topics then meet whenever possible to create a cohesive Wikipedia page as a group.