User:Mattiascollin/antibody sandbox

This is where I will be drafting new content for the Antibody page.

Antibodies are heavy (~150 kDa) globular plasma proteins. The size of an antibody molecule is about 10 nm. They have sugar chains (glycans) added to conserved amino acid residues. In other words, antibodies are glycoproteins. The attached glycans are critically important to the structure and function of the antibody. Among other things the expressed glycans can modulate an antibody's affinity for its corresponding FcR(s). Copied from Antibody

Antibody glycosylation
Here I will start expanding on the glycosylation of immunoglobulins, starting with IgG (Fc and Fab, effector functions, glycan analysis, glycan engineering, interaction with Fc receptors etc). IgA, IgM, IgD, IgE - what is know about composition and function?