User:Mgmswim/sandbox

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Prostate cancer is cancer of the prostate in males. The prostate is a gland in the male reproductive system that surrounds the urethra just below the bladder. Most prostate cancers are slow growing, yet in rare cases can be aggressive. Cancerous cells may spread to other areas of the body, particularly the bones, lymph nodes and brain. Initially, no symptoms my occur or show for years. However, in later stages, symptoms include pain or difficulty urinating, blood in the urine, pain in the pelvis or back, or fatigue, due to low levels of red blood cells. Prostate cancer is normally slow growing and less aggresiive and it is more common for men to die of other causes that are not related to prostate cancer.

- Medication Exposure

ORIGINAL

Some links have been established between prostate cancer and medications, medical procedures, and medical conditions. Statins may also decrease risk.

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Some research had been done in which have shown possible linkage between prostate cancer and medications, medical procedures, and medical conditions. Studies have been done in which have shown how Statins may decrease risk. Statins are a cholesterol lowering medication There have also been studies done in Finland which have shown promising research in prostate cancer when men are on antidiabetic medication.

There has not been many studies done that show certain dugs that increase prostate cancer.

- Infection

ORIGINAL

Prostatitis (infection or inflammation) may increase risk. In particular, infection with the sexually transmitted infections Chlamydia, gonorrhea, or syphilis seems to increase risk.

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Prostatitis (infection or inflammation) may increase risk of the development of prostate cancer. In particular, infection with the sexually transmitted infections Chlamydia, gonorrhea, or syphilis could lead to that increase. These types of inflammation can lead to an inflamed prostate later leading to a higher chance of one being diagnosed with prostate cancer. Inflammation is known as being a huge cause in certain sicknesses because ones immune system is starting to deplete or work very hard in preventing the inflammation from exceeding.

- Environment

ORIGINAL

US war veterans who had been exposed to Agent Orange had a 48% increased risk of prostate cancer recurrence following surgery.

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 * Pesticides

Prostate cancer has more of a genetic linkage than a environmental linkage of occurring. Yet, it has been found that US war veterans who had been exposed to Agent Orange, had a 48% increased risk of prostate cancer recurrence following surgery. In 2012, the FDA had banned the use of BPA in multiple products due to the health affects that BPA was found to cause such as, liver malfunctions. BPA was used in many plastic manufactures. Later studies have shown that there are possible correlation of those who had ingested a high amount of BPA led to an increased risk of prostate cancer.

- Sex

ORIGINAL

Although some evidence from prospective cohort studies indicates that frequent ejaculation may reduce prostate cancer risk, no randomized controlled trials reported this benefit. An association between vasectomy and prostate cancer was found, but causality has not been established.

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- Adding more to Gleason Score (needs a lot more info because of how big of a medical finding it was in diagnosis)

ORIGINAL

The Gleason grading system is used to help evaluate the prognosis and helps guide therapy. A Gleason score is based upon the tumor's appearance. Cancers with a higher Gleason score are more aggressive and have a worse prognosis. Pathological scores range from 2 through 10, with a higher number indicating greater risks and higher mortality.

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 * who developed the gleason score
 * when was it developed
 * why is it so accurate
 * how is it involved in the diagnosis and the severity of the cancer
 * scores of 6 or less are not a huge concern and very good level, 7 is moderate level and can be aggressive, 8-10 means the cancer is very aggressive and at a high stage

The Gleason grading system is used to help evaluate the prognosis and helps guide therapy. A Gleason score is based upon the tumor's appearance. Cancers with a higher Gleason score are more aggressive and have a worse prognosis. Pathological scores range from 2 through 10, with a higher number indicating greater risks and higher mortality.

- Canada

ORIGINAL

Prostate cancer is the third-leading type of cancer in Canadian men. In 2016, around 4,000 died and 21,600 men were diagnosed with prostate cancer.

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- Europe

ORIGINAL

In Europe in 2012, it was the third-most diagnosed cancer after breast and colorectal cancers at 417,000 cases.

In the United Kingdom, it is the second-most common cause of cancer death after lung cancer, where around 35,000 cases are diagnosed every year, of which around 10,000 are fatal.

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SOURCES