User:Micatlan/Holographic laser Doppler imaging





Holographic laser Doppler imaging, or laser Doppler holography refers to computational imaging techniques based on laser interferometry and digital holography used to reveal local dynamics through optical fluctuations analysis.

Medical imaging applications
The eye offers a unique opportunity for the non-invasive exploration of cardiovascular diseases. LDI can measure blood flow in the retina and choroid. In particular, the choroid is a highly vascularized tissue supplying the retinal pigment epithelium and photoreceptors. Yet investigating the anatomy and flow of the choroid remains challenging. LDI provides high-contrast visualization of local blood flow in choroidal vessels in humans, with a spatial resolution comparable to state-of-the-art indocyanine green angiography. Differences in blood pressure drive the flow of blood throughout the circulation. The rate of mean blood flow depends on both blood pressure and the hemodynamic resistance to flow presented by the blood vessels. LDI can enable mapping of the local arterial resistivity index, and the possibility to perform unambiguous identification of retinal arteries and veins on the basis of their systole-diastole variations, and reveal ocular hemodynamics in human eyes.