User:Millstei

Joshua Millstein Assistant Professor Division of Biostatistics Department of Preventive Medicine Keck School of Medicine, USC

During my PhD work in Biostatistics at the University of Southern California (completed in 2005), and throughout my career, my research interests and efforts have focused on problems of high dimensional data, particularly population based genomic and transcriptomic data in the context of complex diseases. This work has included statistical methods development for the analysis of genomic data in the context of animal model, epidemiological, and clinical studies. Areas of statistical methods development have included statistically powerful and computationally efficient approaches for epistasis, eQTL, causal inference, false discovery rates, and copy number alterations in the context of breast cancer and hepatocellular carcinoma. My interests have also included the reconstruction of transcriptional regulatory networks by a variety of techniques including weighted gene coexpression network analysis, Bayesian networks by Markov chain Monte Carlo (MCMC) and optimal approaches, as well as causal inference (mediation) statistical hypothesis tests.