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Arguments for assisted suicide
One argument for assisted suicide is that it reduces prolonged suffering in those with terminal illnesses. When death is imminent (half a year or less) patients can choose to have assisted death as a medical option to shorten what the person perceives to be an unbearable dying process. Pain is mostly not reported as the primary motivation for seeking physician assisted suicide in the United States; the three most frequently mentioned end‐of‐life concerns reported by Oregon residents who took advantage of the Death With Dignity Act in 2015 were: decreasing ability to participate in activities that made life enjoyable (96.2%), loss of autonomy (92.4%), and loss of dignity (78.4%).

Oregon statistics
In 1994, Oregon became the first US state to legalize assisted suicide. A study of hospice nurses and social workers in Oregon reported that symptoms of pain, depression, anxiety, extreme air hunger and fear of the process of dying were more pronounced among hospice patients who did not request a lethal prescription for barbiturates, the drug used for physician assisted death.

A Journal of Palliative Medicine report on patterns of hospice use noted that Oregon was in both the highest quartile of hospice use and the lowest quartile of potentially concerning patterns of hospice use. A similar trend was found in Vermont, where AiD was authorized in 2013.

In Oregon, in hospital death rates are at the lowest in the nation, at home death rates are at the highest in the nation, and violent suicide among hospice patients has been reduced significantly.

In February 2016, Oregon released a report on their 2015 numbers. During 2015, there were 218 people in the state who were approved and received the lethal drugs to end their own life. Of that 218, 132 terminally ill patients ultimately made the decision to ingest drugs, resulting in their death. According to the state of Oregon Public Health Division's survey, the majority of the participants, 78%, were 65 years of age or older and predominately Caucasian, 93.1%. 72% of the terminally ill patients who opted for ending their own lives had been diagnosed with some form of cancer. In the state of Oregon's 2015 survey, they asked the terminally ill who were participating in medical aid in dying, what their biggest end-of-life concerns were: 96.2% of those people mentioned the loss of the ability to participate in activities that once made them enjoy life, 92.4% mentioned the loss of autonomy, or their independence of their own thoughts or actions, and 75.4% stated loss of their dignity (Oregon Death With Dignity Act).

Washington State statistics
An increasing trend in deaths caused from ingesting lethal doses of medications prescribed by physicians was also noted in Washington: from 64 deaths in 2009 to 202 deaths in 2015. Among the deceased, 72% had terminal cancer and 8% had neurodegenerative diseases (including ALS).

United States polls
Polls conducted by Gallup dating back to 1947 positing the question, "When a person has a disease that cannot be cured, do you think doctors should be allowed to end the patient's life by some painless means if the patient and his family request it?" show support for the practice increasing from 37% in 1947 to a plateau of approximately 75% lasting from approximately 1990 to 2005. When the polling question was modified as such so the question posits "severe pain" as opposed to an incurable disease, "legalization" as opposed to generally allowing doctors, and "patient suicide" rather than physician-administered euthanasia, public support was substantially lower, by approximately 10% to 15%.

A poll conducted by National Journal and Regence Foundation found that both Oregonians and Washingtonians were more familiar with the terminology "end-of-life care" than the rest of the country and residents of both states are slightly more aware of the terms palliative and hospice care.

A survey from the Journal of Palliative Medicine found that family caregivers of patients who chose assisted death were more likely to find positive meaning in caring for a patient and were more prepared for accepting a patient's death than the family caregivers of patients who didn't request assisted death.