User:Mitchelchik/Chelerythrine

Anti-Cancer Mechanisms

 * Depending on the form of cancer, Chelerythrine can exhibit different effects on tumor cells, leading to inhibition of tumor growth. These mechanisms include inducing apoptosis, arrest of the cell cycle, promoting autophagy of cancerous cells, and the inhibition of telomerase. It has been found to be a possible anti-cancer agent for liver, gastric, breast, renal, and cervical cancers.

Role as a Protein Kinase C Inhibitor

 * Studies show that Chelerythrine is a specific and potent protein kinase C inhibitor. Due to its inhibitory effects on protein kinase C, it has been found of use against triple-negative breast cancer. By inhibiting protein kinase C, signaling pathways are disrupted, inducing cell cycle arrest.