User:Mmfas13/Magnetic resonance microscopy

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Magnetic resonance microscopy (MRM, μMRI) is magnetic resonance imaging (MRI) at a microscopic level down to the scale of microns. The first definition of MRM was MRI having voxel resolutions of better than 100 μm.

Section: Nomenclature
Magnetic resonance microscopy refers to very high resolution MRI imaging (down to nanometer scale, in some cases comparable with histopathology). The term MR microscopy is most widely used by the High Resolution Magnetic Resonance Imaging department at Duke University, headed by Dr. G. Allan Johnson, and the National High Magnetic Field Lab group at AMRIS, University of Florida/Florida State University.

Section: Differences between MRI and MRM

 * MRM represents a higher evolution of MRI.
 * MRM employs a much stronger magnetic field, which is conducted on a much smaller scale.
 * Resolution: Medical MRI resolution is typically about 1 mm; the desired resolution of MRM is 100 μm or smaller to 10 μm, comparable with histology.
 * Specimen size: Medical MRI machines are designed so that a patient may fit inside. MRM chambers are usually small, typically less than 1 cm3 for the imaging of rats, mice and rodents. BrukerBio Spin Company, Billerica, MA specialises in the supply of different microimaging probes (5 mm – 75 mm) for ex vivo/in vivo imaging of excised biological samples.