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Folliculitis may be caused by the herpes simplex virus. This tends to be tender and resolves without treatment in around ten days. Severe recurrent attacks may be treated with aciclovir and other antiviral agents.

Herpes zoster (the cause of shingles) may also present as folliculitis with painful pustules and crusted spots within a dermatome (an area of skin supplied by a single nerve). It is treated with high-dose aciclovir.